The recommended dosage is dependent on the age, bodyweight and medical condition of the patient, and should be determined by a clinician or dietitian only. The amino acids can be used to supplement both sip and tube feeding. Approximately 3g L-Isoleucine dissolves in 100mls of water at 20°C. It can be added directly to liquid formulae. For powdered formulae, L-Isoleucine is best added to the powder before reconstitution. Flavouring can be added if required. The addition of flavourings to foods for infants under 6 months is not recommended.